What Are Microplastics?
Microplastics are tiny fragments of plastic—typically less than 5 millimeters in size—formed from the breakdown of larger plastic materials or manufactured at microscopic scale for use in industrial and consumer products.
They are now ubiquitous in the environment and have been detected in food, drinking water, and the air. As a result, routine human exposure occurs primarily through ingestion and inhalation.
Unlike many dietary particles, microplastics are chemically stable and resistant to biological degradation. Emerging evidence suggests that some particles can persist within the gastrointestinal tract and interact with the mucosal surface, the microbiome, and host immune signaling pathways.
Understanding how the body encounters, processes, and eliminates these materials is an active area of scientific investigation—and central to modern environmental health research.
But your body isn’t powerless.
It can be supported.
Introducing SEQUESTRA — a science-driven approach designed to support how your body handles modern environmental exposure.*
How SEQUESTRA™ works with your biology
SEQUESTRA™
A Gut-First Framework
The gastrointestinal tract is not just a digestive organ, it is the primary interface between the external environment and the internal body. It is where ingested materials first interact with epithelial barriers, immune signaling pathways, and metabolic regulation. This includes not only nutrients, but also persistent, indigestible materials increasingly present in the modern environment, such as microplastics.
SEQUESTRA is designed around this principle, with a focus on how the gut physiologically handles non-absorbable environmental particles*:
Physical binding and sequestration of select indigestible materials, including microplastics, within the gastrointestinal lumen
Support of normal transit and elimination pathways responsible for clearing non-absorbable residues
Reinforcement of intestinal barrier function and immune–metabolic signaling that may be challenged by chronic, low-level exposure
This approach emphasizes containment, clearance, and control—without overstimulation, forced detoxification, or pharmacologic intervention.*
Mechanism-Driven Formulation
Each ingredient in SEQUESTRA is selected based on*:
Established gastrointestinal physiology relevant to luminal handling of indigestible materials
Peer-reviewed research on biomaterial–gut interactions and barrier function
Safety profiles appropriate for routine, long-term use
Compatibility with the native microbiome and normal digestive processes
Formulations are designed to function independently or as part of a coordinated system, reflecting the interconnected nature of gut biology and the multi-step handling of environmental particulates such as microplastics.*
Quality, Oversight, and Scientific Restraint
SEQUESTRA is*:
Formulated by physician-scientists with backgrounds in gastrointestinal research and diagnostics
Manufactured in GMP-certified facilities
Third-party tested for purity, potency, and contaminants
Supported by batch-specific Certificates of Analysis
We prioritize clean-label formulation, transparent sourcing, and clinically informed dosing—guided by human data where available and restraint where uncertainty remains.*
What This Is — and What It Is Not
SEQUESTRA is not a detox, a cure, or a medical treatment. It does not claim to remove microplastics from the body or alter disease risk.
SEQUESTRA is a science-informed gastrointestinal approach designed to support the body’s natural handling of indigestible environmental materials—including microplastics—within the gut. Our goal is not to override biology, but to work in alignment with it.*